HSP90 INHIBITION DECREASES MITOCHONDRIAL PROTEIN TURNOVER.

Hsp90 inhibition decreases mitochondrial protein turnover.

Cells treated with hsp90 inhibitors exhibit pleiotropic changes, including an expansion of the mitochondrial compartment, accompanied by mitochondrial fragmentation and condensed mitochondrial morphology, with ultimate compromise of mitochondrial integrity and apoptosis.We identified several mitochondrial oxidative phosphorylation complex subunits,

read more

Impacts of Climatic Variation on the Growth of Black Spruce Across the Forest-Tundra Ecotone: Positive Effects of Warm Growing Seasons and Heat Waves Are Offset by Late Spring Frosts

Climate strongly limits the physiological processes of trees near their range limits, leading to increased growth sensitivity.Northeastern North America is experiencing considerable warming, so the growth of trees near the northern treeline represents a key indicator of forest responses to climate change.However, tree-ring series and corresponding

read more

ADVANCED FIRE SUPPRESSION TECHNOLOGIES AT FUEL STORAGE FACILITIES

This article analyses challenges of the fire extinguishing process at fuel storage facilities and looks at modern technologies aimed at extinguishing burning petrochemicals, such as: subsurface foam injection, combined gas and click here powder fire extinguishing technology BiZone, aerosol generator Purga, automatic fire-fighting system USP-01F, fo

read more